BDBM100953 US10189794, Compound I-240::US10618902, Compound I-240::US10774052, Compound I-240::US9695132, I-240
SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(N[C@H]3COC[C@H]3NC(=O)C=C)nc2n(C)c1=O
InChI Key InChIKey=ZIJVLVUPDVUSMA-KGLIPLIRSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 100953
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of FGFR2 (unknown origin) expressed in KATO -III cells assessed as autophosphorylation after 1 hr incubation measured by Mesoscale discove...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 776nMAssay Description:Inhibition of recombinant human tagged FGFR2 using Y10-Sox as substrate in presence of 250 uM ATP by Omnia kinase methodMore data for this Ligand-Target Pair