BDBM100953 US10189794, Compound I-240::US10618902, Compound I-240::US10774052, Compound I-240::US9695132, I-240

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1cc2cnc(N[C@H]3COC[C@H]3NC(=O)C=C)nc2n(C)c1=O

InChI Key InChIKey=ZIJVLVUPDVUSMA-KGLIPLIRSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100953   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM100953(US10189794, Compound I-240 | US10618902, Compound ...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of FGFR2 (unknown origin) expressed in KATO -III cells assessed as autophosphorylation after 1 hr incubation measured by Mesoscale discove...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM100953(US10189794, Compound I-240 | US10618902, Compound ...)
Affinity DataIC50:  776nMAssay Description:Inhibition of recombinant human tagged FGFR2 using Y10-Sox as substrate in presence of 250 uM ATP by Omnia kinase methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed